There certainly are a lot of online business training programs out there. Many of them are quite good, in fact. I take nothing away from those guys. I know many of them personally. But, here's my take...
The Lab is designed to be an "all in one" program. One membership is going to get you access to an entire library of courses covering numerous important skills and topics relevant to you building your online business. Most other courses tackle one topic pretty well, but because it is doesn't cover everything you end up still trying to piece things together and getting suckered in by more shiny objects.
Secondly, The Roadmap is a pretty unique feature that only The Lab has.
Third, massive levels of support and involvement. Many "gurus" might sell a great course, but once you've paid them, they're hard to get ahold of. In my case, when you enroll in the Lab, I consider that's when my work begins. I'm in the Community almost every day. I'm answering emails. I'm involved. I end up on a first name basis with man of my Lab members.